Cartoon Brew provides context:

Fans of Warner Bros. Animaniacs series are quite vocal in their devotion to the old episodes and their desire to see the series return. The Animaniacs Revival Project is a group on Facebook devoted to trying to convince Warner Bros. and Spielberg to produce more episodes. To that end, here’s the opening to Animaniacs re-animated in South Park’s cut-out animation style, created using Flash 8, by UK animaniac “Dr. Toonhattan”.

Well it worked for Betty White.