<?xml version="1.0" encoding="UTF-8" standalone="yes"?><oembed><version><![CDATA[1.0]]></version><provider_name><![CDATA[The Dish]]></provider_name><provider_url><![CDATA[http://dish.andrewsullivan.com]]></provider_url><author_name><![CDATA[Andrew Sullivan]]></author_name><author_url><![CDATA[https://dish.andrewsullivan.com/author/sullydish/]]></author_url><title><![CDATA[Why Dogs Come In All Shapes And&nbsp;Sizes]]></title><type><![CDATA[link]]></type><html><![CDATA[
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<p>Because dogs are a&#0160;<a href="http://ngm.nationalgeographic.com/2012/02/build-a-dog/ratliff-text" target="_self">uniquely malleable</a>&#0160;species:</p>
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<p>[B]ody size, hair length, fur type, nose shape, ear positioning, coat color, and the other traits that together define a breed&#39;s appearance are controlled by somewhere in the neighborhood of 50 genetic switches. The difference between floppy and erect ears is determined by a single gene region in canine chromosome 10, or CFA10. The wrinkled skin of a Chinese shar-pei traces to another region, called HAS2. The patch of ridged fur on Rhodesian ridgebacks? That&#39;s from a change in CFA18. Flip a few switches, and your dachshund becomes a Doberman, at least in appearance. Flip again, and your Doberman is a Dalmatian.</p>
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<p>The reason humans are much more uniform:</p>
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<p>In nature, a physical trait or disease state is usually the product of a complex interaction of many genes, each one making a fractional contribution. Height in humans, for instance, is determined by the interaction of some 200 gene regions.</p>
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