As E.O. Wilson accepts his 2007 TED Prize, he makes a plea on behalf of his constituents, the insects and small creatures, to learn more about our biosphere. We know so little about nature, he says, that we’re still discovering tiny organisms indispensable to life; and yet we’re steadily, methodically, vigorously destroying nature. Wilson identifies five grave threats to biodiversity (a term he coined), and makes his TED wish: that we will work together on the Encyclopedia of Life, a web-based compendium of data from scientists and amateurs on every aspect of the biosphere.